GGSC 310: Genome Structure/Organization
CRN: 41437
Min CR: 3
Schedule Type: Lecture
Instructor: Michael R. Crowley

Prerequisites

Undergraduate level BY 210 Minimum Grade of C and Undergraduate level CH 117 Minimum Grade of C and Undergraduate level CH 118 Minimum Grade of C

Description

This course will cover the general concepts of genomics including gene structure and function, genomic technologies and their applications, and comparative genomics.

GGSC 320: Colloquium Genetics/Genomics
CRN: 41438
Min CR: 1
Schedule Type: Seminar
Instructor: Wioletta Czaja (P)

Description 

Faculty-led seminar course that exposes students to cutting edge research topics and career opportunities in the fields of genetics and genomics. Students will read assigned articles and be prepared for discussion.

GGSC 380: UG Research Genetics/Genomics
CRN: 41439
Min CR: 1
Max CR: 3
Schedule Type: Seminar
Instructor: Wioletta Czaja (P)

Description

Research project for non-GGS Honors students under the supervision of a faculty sponsor. May be repeated for a total of 9 semester credit hours in a 2 or 3 semester period.

GGSC 390: Hon Research Genetics/Genomics
CRN: 41440
Min CR: 1
Max CR: 3
Schedule Type: Undergraduate Research
Instructor: Wioletta Czaja (P)

Description

Research project for GGS Honors students under the supervision of a faculty sponsor. May be repeated for a total of 9 semester credit hours in a 2 or 3 semester period.

GGSC 410: Genetics of Disease
CRN: 41441
Min CR: 3
Schedule Type: Lecture
Instructor: Jon D. Sharer (P)

Prerequisites 

Undergraduate level BY 210 Minimum Grade of C and Undergraduate level CH 117 Minimum Grade of C and Undergraduate level CH 118 Minimum Grade of C and (Undergraduate level GGSC 310 Minimum Grade of C or Undergraduate level BY 311 Minimum Grade of C)

Description

This course will focus on the medical applications of genetics and genomic technologies. Topics covered include, but are not limited to major forms of chromosomal abnormalities, mutations and genetic disorders, genetic risk assessment and population genetics, and genomic approaches to diagnosis.

GGSC 435: Zebrafish Models
CRN: 43713
Min CR: 3
Schedule Type: Lecture
Instructor: Ryan M. Centini (P)

Prerequisites 

Undergraduate level CH 117 Minimum Grade of C and Undergraduate level CH 118 Minimum Grade of C and Undergraduate level BY 210 Minimum Grade of C and Undergraduate level GGSC 310 Minimum Grade of C

Description

This course will focus on the biology, husbandry, and management of zebrafish used as an animal model of human disease in biomedical research. Topics will include anatomy, physiology, systems design, water quality management, behavior and enrichment, spawning and larviculture, nutrition and live feeds, diseases, quarantine, biosecurity, and regulatory compliance.

GGSC 470: Pharmacogenetics
CRN: 43715
Min CR: 3
Schedule Type: Lecture
Instructor: Tatjana Coric (P)

Prerequisites 

Undergraduate level CH 117 Minimum Grade of C and Undergraduate level CH 118 Minimum Grade of C and Undergraduate level BY 210 Minimum Grade of C and Undergraduate level GGSC 310 Minimum Grade of C

Description

Most of the drugs that we use today were developed with the assumption that the same drug will work equally well in all the patients that have the same disease. However, there is considerable variability between individual patients - both in the therapeutic response and the adverse effects of the same drug - that is largely determined by the differences in their genotypes. Pharmacogenetics and pharmacogenomics study the genetic determinants of drug response, with the goal to identify genetic variants that can be used to predict the efficacy of a particular drug in a particular patient and to avoid adverse drug reactions. This will ultimately enable implementation of personalized treatment options, by selecting the drugs that will have the best efficacy and the least toxicity for each individual patient. This course will introduce students to the basic principles of pharmacogenetics, demonstrate examples of drug/genotype interactions, highlight the available pharmacogenetic resources, and discuss the potential benefits, as well as limitations and challenges of pharmacogenetics and personalized medicine.

GGSC 491: Personalized Genomic Medicine
CRN: 41442
Min CR: 3
Schedule Type: Lecture Capstone Course
Instructor: Deeann Wallis-Schultz (P)

Prerequisites 

Undergraduate level BY 210 Minimum Grade of C and Undergraduate level CH 117 Minimum Grade of C and Undergraduate level CH 118 Minimum Grade of C and (Undergraduate level GGSC 310 Minimum Grade of C or Undergraduate level BY 311 Minimum Grade of C)

Description

Significant developments in the fields of genetics and genomics are making it possible to tailor medical care to the specific needs of patients. New diagnostic tests, up to and including whole genome sequencing, provide increasingly powerful tools for the identification of the genetic basis of both rare and common disorders. Better understanding of the causes of disease are permitting drugs to be developed that precisely target disease mechanisms, increasing the efficacy and avoiding side effects. These and other new advanced are leading to major changes in healthcare delivery and provide the consumer with new opportunities and complex choices. This course will focus on exploring state-of-the-art genetic, genomic, and informatic tools now available to enable personalization of healthcare. Capstone course (GGS majors). Students that enroll in this class as their capstone experience are expected to do writing or presentation assignments to fulfill their capstone requirement.

GGSC 610: Generics of Disease
CRN: 42202
Min CR: 3
Schedule Type: Lecture 
Instructor: Jon D. Sharer (P)

Description

This course will focus on the medical applications of genetics and genomic technologies. Topics covered include, but are not limited to major forms of chromosomal abnormalities, mutations and genetic disorders, genetic risk assessment and population genetics, and genomic approaches to diagnosis.

GGSC 635: Zebrafish Models
CRN: 43714
Min CR: 3
Schedule Type: Lecture 
Instructor: Ryan M. Centini (P)

Description

This course will focus on the biology, husbandry, and management of zebrafish used as an animal model of human disease in biomedical research. The course is suitable for undergraduate and graduate students. Topics will include anatomy, physiology, systems design, water quality management, behavior and enrichment, spawning and larviculture, nutrition and live feeds, diseases, quarantine, biosecurity, and regulatory compliance.

GGSC 670: Pharmacogenetics
CRN: 43716
Min CR: 3
Schedule Type: Lecture 
Instructor: Tatjana Coric (P)

Description

Most of the drugs that we use today were developed with the assumption that the same drug will work equally well in all the patients that have the same disease. However, there is considerable variability between individual patients - both in the therapeutic response and the adverse effects of the same drug - that is largely determined by the differences in their genotypes. Pharmacogenetics and pharmacogenomics study the genetic determinants of drug response, with the goal to identify genetic variants that can be used to predict the efficacy of a particular drug in a particular patient and to avoid adverse drug reactions. This will ultimately enable implementation of personalized treatment options, by selecting the drugs that will have the best efficacy and the least toxicity for each individual patient. This course will introduce students to the basic principles of pharmacogenetics, demonstrate examples of drug/genotype interactions, highlight the available pharmacogenetic resources, and discuss the potential benefits, as well as limitations and challenges of pharmacogenetics and personalized medicine.

GGSC 691: Personalized Genomic Medicine
CRN: 42203
Min CR: 3
Schedule Type: Lecture 
Instructor: Deeann Wallis-Schultz (P)

Description

Significant developments in the fields of genetics and genomics are making it possible to tailor medical care to the specific needs of patients. New diagnostic tests, up to and including whole genome sequencing, provide increasingly powerful tools for the identification of the genetic basis of both rare and common disorders. Better understanding of the causes of disease are permitting drugs to be developed that precisely target disease mechanisms, increasing the efficacy and avoiding side effects. These and other new advanced are leading to major changes in healthcare delivery and provide the consumer with new opportunities and complex choices. This course will focus on exploring state-of-the-art genetic, genomic, and informatic tools now available to enable personalization of healthcare.